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Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to exercise in adults with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Children should not usually take sildenafil, but in some cases, a doctor may decide that sildenafil (Revatio) is the best medication to treat a child's condition. Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily.
If you are taking sildenafil to treat erectile dysfunction, you should know that it does not cure erectile dysfunction or increase sexual desire. Sildenafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV).
If you are taking sildenafil to treat erectile dysfunction, follow your doctor's directions and the guidelines in this paragraph. Take sildenafil as needed before sexual activity. The best time to take sildenafil is about 1 hour before sexual activity, but you can take the medication any time from 4 hours to 30 minutes before sexual activity. Sildenafil usually should not be taken more than once every 24 hours. If you have certain health conditions or are taking certain medications, your doctor may tell you to take sildenafil less often. You can take sildenafil with or without food. However, if you take sildenafil with a high-fat meal, it will take longer for the medication to start to work.
If you are taking sildenafil to treat PAH, follow your doctor's directions and the guidelines in this paragraph. You will probably take sildenafil three times a day with or without food. Take sildenafil at around the same times every day, and space your doses about 4 to 6 hours apart.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sildenafil exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
If you are taking sildenafil for erectile dysfunction, your doctor will probably start you on an average dose of sildenafil and increase or decrease your dose depending on your response to the medication. Tell your doctor if sildenafil is not working well or if you are experiencing side effects.
If you are taking sildenafil for PAH, you should know that sildenafil controls PAH but does not cure it. Continue to take sildenafil even if you feel well. Do not stop taking sildenafil without talking to your doctor.
If you are taking sildenafil for PAH, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Some patients experienced a sudden loss of some or all of their vision after they took sildenafil or other medications that are similar to sildenafil. The vision loss was permanent in some cases. It is not known if the vision loss was caused by the medication. If you experience a sudden loss of vision while you are taking sildenafil, call your doctor immediately. Do not take any more doses of sildenafil or similar medications such as tadalafil (Cialis) or vardenafil (Levitra) until you talk to your doctor.
There have been reports of heart attack, stroke, irregular heartbeat, bleeding in the brain or lungs, high blood pressure, and sudden death in men who took sildenafil for erectile dysfunction. Most, but not all, of these people had heart problems before taking sildenafil. It is not known whether these events were caused by sildenafil, sexual activity, heart disease, or a combination of these and other causes.Talk to your doctor about the risks of taking sildenafil.
Some patients experienced a sudden decrease or loss of hearing after they took sildenafil or other medications that are similar to sildenafil. The hearing loss usually involved only one ear and did not always improve when the medication was stopped. It is not known if the hearing loss was caused by the medication. If you experience a sudden loss of hearing, sometimes with ringing in the ears or dizziness, while you are taking sildenafil, call your doctor immediately. If you are taking sildenafil (Viagra) for erectile dysfunction, do not take any more doses of sildenafil (Viagra) or similar medications such as tadalafil (Cialis) or vardenafil (Levitra) until you talk to your doctor. If you are taking sildenafil (Revatio) for PAH, do not stop taking your medication until you talk to your doctor.
To help clear things up, we took a closer look at many of the top services that can prescribe and ship sildenafil directly to your home so that you can have the facts that you need to get your ED treatment started.
To purchase generic Viagra (sildenafil) and brand-name Viagra through Optum Store, you must fill out a questionnaire, upload a photo ID, and provide a recent blood pressure reading, which will then be evaluated by a licensed physician in the United States who can determine if sildenafil could treat your ED symptoms.
Sildenafil is in a class of medications called PDE5 inhibitors. These drugs restrict the action of phosphodiesterase enzymes, which break down cyclic guanosine monophosphate. This is a type of molecule that relaxes smooth muscle tissue in the body, such as those in the blood vessels that allow the penis to become erect. Taking sildenafil improves circulation by helping the arteries relax enough to fill more easily with blood.
A 4-year study published in 2007 found that sildenafil is generally safe to use over the long term. Other data pulled from clinical trials in 2016 noted that sildenafil is effective without severe side effects regardless of age.
While generic sildenafil and Viagra are equally safe and effective, the medications have one key difference: price. Viagra costs around $60 to $70 per tablet. Generic sildenafil can range from $7 to $18 per pill, depending on the manufacturer and dose.
In the United States, sildenafil for ED or PH requires a prescription. The United Kingdom allows for over-the-counter sales of the drug, in part to discourage the market for fake sildenafil. Sildenafil is one of the most commonly counterfeited drugs in the world.
The only real food interaction with generic Viagra is grapefruit and grapefruit juice. These products can raise the levels of sildenafil in your body but can also delay the time the drug takes effect.
Similar to grapefruit, medications known as cytochrome P450 (CP450) inhibitors and substrates can delay how long it takes sildenafil to work and can increase your chance of side effects. CP450 inducers, such as modafinil, reduce the effects of sildenafil if taken at the same time.
The normal starting dose, in men who have not taken sildenafil before, is one 50mg tablet. Subsequent doses can be adjusted up to a maximum of 100mg as a single dose, or down to 25mg, depending on response. Most men find 50mg sufficient. Sildenafil should not be taken more than once in 24 hours.
All men with erectile dysfunction should consult a doctor face-to-face before buying sildenafil tablets online. Sildenafil is not suitable for all men, particularly men who have severe heart disease or a history of stroke. Some prescribed medicines interact with sildenafil, most notably medicines called nitrates, used to treat angina and heart disease. 041b061a72